Related Experiment Video
Updated: Aug 26, 2026
Laparoscopic Repair of Para-Esophageal Hernia Using Absorbable Biosynthetic Mesh
Published on: September 11, 2021
Neonatal gastric perforation: review of 23 years' experience
Cem Sultan Kara1, Zekeriya Ilçe, Sinan Celayir
1Department of Pediatric Surgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
Insights
Neonatal gastric perforation (GP) is a serious condition with a high mortality rate. Early diagnosis and prompt management are crucial for improving outcomes in affected infants.
Area of Science:
- Neonatal surgery
- Pediatric gastroenterology
- Surgical pathology
Background:
- Gastric perforation (GP) in neonates is a rare but life-threatening surgical emergency.
- The condition requires prompt diagnosis and intervention to improve survival rates.
Purpose of the Study:
- To review the clinical experience of treating 13 neonates with gastric perforation (GP) over a 23-year period.
- To analyze patient demographics, perforation characteristics, treatment modalities, and outcomes.
Main Methods:
- Retrospective review of medical records for 13 neonates diagnosed with GP.
- Data collected included: gender, weight, gestational age, age at admission, associated anomalies, perforation site, surgical procedure, and clinical outcome.
- Statistical analysis of collected data.
Main Results:
- The study included 11 boys and 2 girls, with 45% being preterm infants.
- The most common surgical intervention was gastrorrhaphy with drainage (12 patients).
- The overall mortality rate was high at 53.8% (7 out of 13 patients).
Conclusions:
- Early diagnosis and management before metabolic deterioration significantly improved prognosis.
- Further comparative investigation into the presentation and surgical findings in premature versus full-term neonates is warranted.
- The etiology of gastric perforation may differ between preterm and full-term infants.
Purpose:
To review our experience of treating 13 neonates with gastric perforation (GP) over the past 23 years.
Methods:
The records of all 13 patients were reviewed, noting gender, weight, gestational age, age at admission, associated anomalies, site of perforation, type of operation, and clinical outcome.
Results:
There were 11 boys and 2 girls, with a mean body weight of 2 375 g, including 4 (45%) preterm infants. The mean age at admission was 3.2 days. Three (23%) infants had associated anomalies. Perforation occurred in the lesser curvature and anterior wall in 3 (23%) infants, at the greater curvature and anterior wall in 2 (15.4%), in necrosis of anterior wall in 1 (7.7%), at the esophageal junction and posterior wall in 2 (15.4%), at the lesser curvature and posterior wall in 1 (7.7%), at the lesser curvature and esophageal junction in 1 (7.7%), and the site was not specified in 3 (23%). Twelve patients were treated with gastrorrhaphy and drainage, and 1 was treated with gastrorrhaphy alone. Three patients required additional gastrostomy. Mortality was 53.8% (n = 7). Early diagnosis and management before clinical deterioration of the metabolic status improved the prognosis.
Conclusion:
The pattern of presentation and surgical findings should be investigated comparatively in premature and full-term neonates, as the etiology of this condition is likely to differ in these two gestational groups.
Related Concept Videos
01:28Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
01:22Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
01:25Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
01:15Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...