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Updated: Aug 26, 2026

Modified Radical Neck Dissection for Cervical Metastasis
Published on: February 20, 2026
Postoperative complications after chemoradiation for advanced head and neck cancer
Eva Proctor1, K Thomas Robbins, Francisco Vieira
1Department of Otolaryngology/Head and Neck Surgery, University of Tennessee, Memphis, College of Medicine, Memphis, Tennessee, USA.
Background:
To compare the rate of postoperative complications of patients with advanced head and neck cancer treated with the chemoradiation protocol "RADPLAT" with that of a similar cohort of patients treated with primary surgery.
Methods:
We retrospectively analyzed 50 patients treated with RADPLAT and 50 patients treated with primary surgery.
Results:
The rates of complications for local wound problems were 54% and 42%, respectively, for the RADPLAT cohort and the primary surgery cohort. However, the rate of local complications for the subset of RADPLAT patients undergoing clean-contaminated surgery was 69% (p =.305). The rates of complications for medical (systemic) problems were 10% and 12%, respectively, for RADPLAT versus primary surgery patients. There was no significant difference in hospitalization time between the groups.
Conclusions:
Among patients with advanced head and neck cancer, surgical complications are high but not significantly different between patients undergoing the chemoradiation protocol "RADPLAT" and those undergoing primary surgery.
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