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Updated: Aug 26, 2026

External Excitation of Neurons Using Electric and Magnetic Fields in One- and Two-dimensional Cultures
Published on: May 7, 2017
Field stimulation of 2-D sheets of excitable tissue
1Department of Biomedical Engineering, Duke University, P.O. Box 90281, 136 Hudson Engineering Bldg., Durham, NC 27708-0281, USA. roger.barr@duke.edu
Abstract:
This paper develops equations for the transmembrane potentials (Vm) that occur in two-dimensional (2-D) sheets of tissue in response to field stimulation from an electrode near but not on the surface of the tissue. Comparison of results with those for one dimension shows that an additional term is present in the 2-D equations that influences the evolution of Vm in the interval between the end of the stimulus and the active propagation that may follow. The results provide an analytical framework for understanding Vm in response to field stimulation in two dimensions, both during the tissue's critical linear phase and thereafter.

