Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurogenesis and neuroadaptation.

David V Schaffer1, Fred H Gage

  • 1Department of Chemical Engineering and the Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720-1462, USA. schaffer@cchem.berkeley.edu

Neuromolecular Medicine
|March 6, 2004
PubMed
Summary

Adult neurogenesis, the birth of new neurons in the adult brain, plays key roles in neural plasticity. Research explores its functions in learning, memory, mood, and brain injury recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression-linked promoter selection (ELiPS) engineers short, strong ubiquitous promoters for gene therapy applications.

bioRxiv : the preprint server for biology·2026
Same author

Optogenetic WNT signaling drives germ layer self-organization in a human gastruloid model.

bioRxiv : the preprint server for biology·2026
Same author

Directed evolution of novel AAV capsids for enhanced delivery to mouse and human Schwann cells.

Molecular therapy. Nucleic acids·2026
Same author

Adeno-associated virus serotype 9 structural heterogeneity and stability characterized by charge detection mass spectrometry.

Molecular therapy. Methods & clinical development·2025
Same author

Ocular Delivery of Viral Vectors for Retinal and Choroidal Vascular Diseases: A Review.

American journal of ophthalmology·2025
Same author

Nickase fidelity drives EvolvR-mediated diversification in mammalian cells.

Nature communications·2025

Area of Science:

  • Neuroscience
  • Cell Biology

Background:

  • Adult neurogenesis is a recognized form of neural plasticity in the adult nervous system.
  • Emerging research investigates the functional significance of this neuroadaptive process.

Purpose of the Study:

  • To elucidate the functional roles and consequences of adult neurogenesis.
  • To bridge molecular and systems-level understanding of neurogenesis and behavior.

Main Methods:

  • Molecular-level investigations into signaling factors regulating stem cell function.
  • Systems and behavioral analyses to link neurogenesis with behavior.

Main Results:

  • Identified potential functions of adult hippocampal neurogenesis.
  • Linked neurogenesis to learning, memory, environmental adaptation, mood regulation, and injury response.

Conclusions:

  • Convergence of molecular and systems approaches is crucial for understanding neurogenesis.
  • New methodologies will enhance insights into neuroadaptive roles and neuroregeneration potential.

Related Experiment Videos