Related Experiment Video
Updated: Aug 26, 2026

Ascending Aortic Constriction in Rats for Creation of Pressure Overload Cardiac Hypertrophy Model
Published on: June 29, 2014
Influence of 2G-hypergravity on the right atrium secretory cardiomyocytes of rats
L S Pogodina1, M V Shornikova, Yu S Chentsov
1Lomonosov Moscow State University, Biological Faculty, Moscow, Russia. lpogod@mail.ru
Abstract:
For elucidation of secretory cardiomyocytes adaptation to prolonged and repeated influence of changed gravity the ultrastructural and morphometrical analysis of right atrium cells was made in rats after they were exposed to primary and repeated 2G-centrifugation in ground-based experiment. It was found prolonged 2G-hypergravity resulted in hypertrophy of right atrium cardiomyocytes and stimulated of their mitochondrial associative activity and granular secretion; repeated influence induced changes differed from those after single influence.

