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Updated: Aug 26, 2026

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
Ovarian papillary cystadenocarcinomas in a green iguana (Iguana iguana)
B A Stacy1, J D Vidal, A Osofsky
1Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA 95616, USA.
Abstract:
The clinical, gross morphological and histological characteristics of bilateral ovarian papillary cystadenocarcinomas in an adult female green iguana (Iguana iguana) are documented in this report. Histologically, the tumour consisted of an invasive mass of small glandular structures, irregular arboriform papillae and cystic structures arising from the ovarian surface epithelium. Metastatic implants were extensively disseminated along the serosa of the coelomic viscera, mesentery and fat bodies. Tumour morphology and metastatic behaviour indicated a close resemblance to cystadenocarcinoma in other species. Primary ovarian neoplasia is rare in reptiles; documented cases include tumours arising from surface epithelium, germ cells and sex cord stroma.
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