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Updated: Aug 8, 2026

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation
10:52

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IGF-I regulates caveolin 1 and IRS1 interaction in caveolae

Danilo Panetta1, Claudia Biedi, Silvia Repetto

  • 1Department of Endocrinology and Metabolism, University of Genova, Genoa, Italy.

Biochemical and Biophysical Research Communications
|March 9, 2004
PubMed
Summary

Insulin-like growth factor I (IGF-I) signaling is concentrated in caveolae. This study shows that IRS1 also localizes and is phosphorylated in caveolae, interacting with caveolin 1 upon IGF-I stimulation.

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