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Totally synthetic analogues of siastatin B. I. Optically active 2-acetamidopiperidine derivatives
1Institute of Microbial Chemistry, Tokyo, Japan.
The Journal of Antibiotics
|June 1, 1992
Abstract:
Totally synthetic analogues of siastatin B, optically active 2-acetamido-3,4,5-trihydroxypiperidines having the nitromethyl, aminomethyl and carboxyl branched groups at C-5 have been obtained from D-ribono-1,4-lactone by a stereospecific convergent method. Some analogues showed inhibitory activity against some glycosidases.