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Growth, Purification, and Titration of Oncolytic Herpes Simplex Virus
Published on: May 13, 2021
Human monoclonal antibody fragment specific for glycoprotein G in herpes simplex virus type 2 with applications for
Francesca Bugli1, Stefania Manzara, Riccardo Torelli
1Istituto di Microbiologia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Journal of Clinical Microbiology
|March 9, 2004
Abstract:
A combinatorial library was used to select a human monoclonal antibody fragment (Fab) with high affinity for G glycoprotein in herpes simplex virus type 2 (HSV-2). Tests with 112 clinical specimens demonstrated successful discrimination between HSV-2 and HSV-1, showing the potential of Fab as a low-cost tool for HSV subtyping in clinical diagnosis.
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