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Updated: Aug 25, 2026
A Mouse Model for Laser-induced Choroidal Neovascularization
Published on: December 27, 2015
Laser treatment for neovascular formation
1Angiology, PUCamp, Medicine-Campinas, Brasil. braskin@terra.com.br
Background And Objectives:
Neovascular formation or matting [Davis and Duffy, J Dermatol Surg Oncol 1990; 16:327; Folkman and Klagsbrun, Science 1987;235:442; Weiss et al., Lasers Surg Med 1996;8:40-41] is a complex problems for doctors to treat. It was done by two different kinds of lasers, 532 nm [Silver and Livshots, Cosmetic Dermatol 1996;9:61; Adrian, Dermatol Surg 1998; 24:19] and 1,064 nm [Weiss and Weiss, Dermatol Surg 1999; 12:399-402] Nd:Yag laser. This study was carried out to discover which had better results on the treatment of this pathology.
Study Design/Materials And Methods:
Thirty-six patients underwent a monthly treatment, two sessions for neovascular formation by the 532 nm diode laser and the 1,064 nm [Weiss and Weiss, Dermatol Surg 1999;12:399-402] Nd:Yag laser. A comparative study was done by digital photography pre and post laser, 1 month after the second treatment by the two methods of evaluation, clinical percent clearance and by mathematically counting the number of vessels.
Results:
There was a significant reduction of the number of capillaries in the affected areas treated by both lasers, mainly in the 1,064 Nd:Yag group.
Conclusions:
The association of 3 and 10 mm spot size of the 1,064 nm laser group had better results compared with the 532 nm laser for matting treatment.
