Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Focus on aripiprazole.

Ben Green1

  • 1Cheadle Royal Hospital, and Honorary Senior Lecturer, University of Liverpool, UK. drbengreen@hotmail.com

Current Medical Research and Opinion
|March 10, 2004
PubMed
Summary
This summary is machine-generated.

Aripiprazole, an antipsychotic, is effective for schizophrenia and shows promise for bipolar disorder. It offers a favorable side-effect profile compared to haloperidol.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of positioning error in double displacement Talbot lithography.

Optics express·2025
Same author

Public perceptions of the Hippocratic Oath in the U.K. 2023.

BMC medical ethics·2024
Same author

Predictive Value of Physiological Values and Symptom Scores for Exacerbations in Bronchiectasis and Chronic Obstructive Pulmonary Disease With Frequent Exacerbations: Longitudinal Observational Cohort Study.

Interactive journal of medical research·2024
Same author

Respiratory Pathogens at Exacerbation in Chronic Bronchitis With Airway Bacterial Colonisation: A Cohort Study.

The clinical respiratory journal·2024
Same author

UK research priority setting for childhood neurological conditions.

Developmental medicine and child neurology·2024
Same author

Successful introgression of wMel Wolbachia into Aedes aegypti populations in Fiji, Vanuatu and Kiribati.

PLoS neglected tropical diseases·2024

Area of Science:

  • Neuroscience
  • Pharmacology
  • Psychiatry

Background:

  • Aripiprazole is a neuroleptic medication targeting dopamine and serotonin receptors.
  • It exhibits high affinity for D(2)- and D(3)-receptors and dopamine autoreceptors.
  • Possesses partial agonist activity at serotonin 5-HT(1A)-receptors and antagonist activity at 5-HT(2A)-receptors.

Purpose of the Study:

  • To provide an overview of recent research on aripiprazole.
  • To examine its efficacy in treating schizophrenia.
  • To explore its potential in managing bipolar disorder.

Main Methods:

  • Literature review of recently published research.
  • Analysis of aripiprazole's pharmacological profile.
  • Examination of clinical applications and dosing guidelines.

Related Experiment Videos

Main Results:

  • Aripiprazole is approved for schizophrenia treatment.
  • It is under investigation for bipolar disorder treatment.
  • Demonstrates a potentially better side-effect profile than haloperidol.

Conclusions:

  • Aripiprazole is a valuable antipsychotic with a distinct receptor-binding profile.
  • Its efficacy in schizophrenia and potential in bipolar disorder warrant further investigation.
  • The drug's side-effect profile may offer advantages over older antipsychotics.