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Design, synthesis and structure-activity relationship of novel RXR-selective modulators
Pierre-Yves Michellys1, Jennifer D'Arrigo, Timothy A Grese
1Department of Medicinal Chemistry, Ligand Pharmaceuticals Incorporated, 10275 Science Center Drive, San Diego, CA 92121, USA. pmichellys@gnf.org
Bioorganic & Medicinal Chemistry Letters
|March 10, 2004
Abstract:
The synthesis and in vitro characterization of novel RXR-selective ligands possessing various substituted 1-benzofuran or 1-benzothiophene moieties are described.