Adenocarcinoma of unknown origin in a patient with primary intestinal lymphangiectasia

This manuscript describes the operational procedures and precautions to probe the potential common pathogenic mechanisms linking primary Sjogren's syndrome and lung adenocarcinoma through bioinformatics analysis and experimental...

Source: Laboratory of Lynne O' Connell — Boston College
When a solid compound is dissolved in a solvent, the freezing point of the resulting solution is lower than that of the pure solvent. This phenomenon is known as freezing-point depression, and the change in temperature is directly related to the molecular weight of the solute. This experiment is designed to find the identity of an unknown compound by using the phenomenon of freezing-point depression to determine its molecular...

Patient-derived organoid cultures of pancreatic ductal adenocarcinoma are a rapidly established 3-dimensional model that represent epithelial tumor cell compartments with high fidelity, enabling translational research into this lethal malignancy. Here, we provide detailed methods to establish and propagate organoids as well as to perform relevant biological assays using these...

Source: Lara Al Hariri and Ahmed Basabrain at the University of Massachusetts Amherst, MA, USA

Source: Lara Al Hariri at the University of Massachusetts Amherst, MA, USA

Aldehydes and Ketones
Aldehydes and ketones have a carbonyl group (C=O) as a functional group. A ketone has two alkyl or aryl groups attached to the carbonyl carbon (RCOR’). The simplest ketone is acetone, which has two methyl groups attached to the carbonyl carbon (CH3COCH3).
An aldehyde is similar to a ketone, except that instead of two side groups connected to the carbonyl carbon, they have at least one hydrogen (RCOH). The simplest aldehyde is formaldehyde (HCOH), as it has two...