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Updated: Aug 25, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Effectiveness of radiofrequency ablation for hepatocellular carcinomas larger than 3 cm in diameter
Ronnie T P Poon1, Kelvin K C Ng, Chi-Ming Lam
1Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam, Hong Kong, People's Republic of China. poontp@hkucc.hku.hk
Hypothesis:
Radiofrequency ablation is a safe and effective treatment for hepatocellular carcinomas 3.1 to 8.0 cm in diameter.
Design:
Case series with prospective data collection.
Setting:
Tertiary referral center.
Patients:
Eighty-six patients with hepatocellular carcinoma treated with radiofrequency ablation from May 1, 2001, to December 31, 2002, were placed into categories of those with tumors 3 cm or smaller (group 1, n = 51) and those with tumors 3.1 to 8.0 cm (group 2, n = 35) in diameter.
Interventions:
Radiofrequency ablation was performed with a single or cluster cool-tip electrode. The choice of treatment route was based on tumor size and position.
Main Outcome Measures:
Complication, treatment mortality, and complete ablation rates.
Results:
Radiofrequency ablation was performed percutaneously in 26 patients in group 1 and 9 patients in group 2, with laparoscopy in 2 patients in group 1 and 1 patient in group 2, and with open operation in 23 patients in group 1 and 25 patients in group 2. The complication rates were 12% and 17% in group 1 and group 2, respectively (P =.48); treatment mortality rates were 0% and 3%, respectively (P =.41). Complete ablation rates after a single session of ablation assessed by means of computed tomography 1 month after treatment were 94% and 91% in group 1 and group 2, respectively (P =.68).
Conclusion:
Radiofrequency ablation is a safe and effective treatment for patients with hepatocellular carcinomas 3.1 to 8.0 cm in diameter.
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