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Updated: Aug 25, 2026

A Preclinical Murine Model of Hepatic Metastases
Published on: September 27, 2014
Merkel cell carcinoma metastatic to the head of the pancreas
James R Ouellette1, Lakeisha Woodyard, Laszlo Toth
1Department of Surgery, Wright State University School of Medicine, Dayton, Ohio, USA. jrouellette@earthlink.net
Context:
Merkel cell carcinoma is an aggressive cutaneous tumor without clearly defined treatment and high propensity for metastasis.
Case Report:
This case describes a sixty four year old presenting with obstructive jaundice approximately two years after having a Merkel cell carcinoma resected from his finger. He underwent a successful pancreaticoduodenectomy with pathology confirming metastatic Merkel cell carcinoma. This report reviews the history, presentation, and current treatment recommendations for Merkel cell carcinoma.
Conclusions:
We propose that resection of metastases from Merkel cell carcinoma may confer a survival advantage and should be strongly considered, particularly if isolated.
