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Published on: January 13, 2026
Pediatric intracranial complications of central venous catheter placement
Caitlin Anderson1, Patrick C Graupman, Walter A Hall
1Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN, USA.
Insights
Misplaced central venous catheters in critically ill children can cause severe injury or death. Awareness of central venous catheter malpositioning is crucial to prevent fatal intracranial complications, as shown in two case studies.
Area of Science:
- Pediatric critical care medicine
- Medical device safety
- Neurocritical care
Background:
- Central venous catheters (CVCs) are vital for managing critically ill pediatric patients.
- Proper CVC placement is essential to avoid serious complications.
- Malpositioned CVCs can lead to widespread organ system damage.
Observation:
- Two pediatric cases are presented involving central venous catheter misplacement.
- Complications arose from the incorrect positioning of the CVCs.
- Intracranial pathology was a severe outcome in both cases.
Findings:
- Central venous catheter malpositioning can result in devastating intracranial pathology.
- This complication can affect single or multiple organ systems.
- One of the presented cases resulted in a fatal outcome.
Implications:
- Highlights the critical need for vigilance in CVC placement in pediatric intensive care.
- Emphasizes the potential for severe neurological injury and mortality due to CVC malposition.
- Underscores the importance of advanced imaging and confirmation techniques for CVC placement.
Abstract:
Central venous catheters are essential in the medical management of critically ill pediatric patients. Medical practitioners should be aware of the potential for misplacement of these devices as such complications may result in serious injury and possible death. Catheter malpositioning is not limited to any particular site and may have far-reaching consequences that affect a single or multiple organ systems. We present two cases where central venous catheter positioning led to complications that resulted in intracranial pathology which was fatal in one case.
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