Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Intraocular triamcinolone for diffuse diabetic macular edema].

R F Degenring1, I Kreissig, J B Jonas

  • 1Fakultät für Klinische Medizin Mannheim der Ruprecht-Karls-Universität Heidelberg, Universitäts-Augenklinik Mannheim. robert.degenring@augen.ma.uni-heidelberg.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|March 10, 2004
PubMed
Summary

Intravitreal injections of triamcinolone acetonide improved visual acuity in patients with diffuse diabetic macular edema. While effective, some patients developed secondary ocular hypertension.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Influence of Diabetes, Hypertension, and Hyperlipidemia on the Onset of Age-Related Macular Degeneration in North China: The Kailuan Eye Study.

Biomedical and environmental sciences : BES·2022
Same author

Sympathetic ophthalmia in vater association combined with persisting hyperplastic primary vitreous after cyclodestructive procedure.

European journal of ophthalmology·2017
Same author

A novel frameshift deletion in the COL1A1 gene identified in a Chinese family with osteogenesis imperfecta.

Genetics and molecular research : GMR·2015
Same author

Arterial pre-hypertension and hypertension in intracranial versus extracranial cerebrovascular stenosis.

European journal of neurology·2014
Same author

[Not Available].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2014
Same author

[Entropion: objective and subjective evaluation of two different surgical procedures].

Klinische Monatsblatter fur Augenheilkunde·2014

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Pharmacology

Background:

  • Diabetic macular edema is a leading cause of vision loss in diabetic patients.
  • Diffuse diabetic macular edema poses significant treatment challenges.
  • Intravitreal corticosteroid injections are explored for managing macular edema.

Purpose of the Study:

  • To assess the efficacy of intravitreal triamcinolone acetonide in improving visual acuity.
  • To evaluate the safety profile of this treatment for diabetic macular edema.

Main Methods:

  • A prospective, interventional study involving 32 eyes of 26 patients with diffuse diabetic macular edema.
  • Intravitreal injection of 25 mg triamcinolone acetonide administered.
  • Visual acuity and intraocular pressure monitored over a mean follow-up of 6.8 months.

Related Experiment Videos

Main Results:

  • Significant visual acuity improvement observed at 4 and 8 weeks post-injection (p=0.009 and p=0.006, respectively).
  • 81.3% of eyes gained visual acuity, with improvements sustained up to 6 months.
  • 31.2% of eyes developed steroid-induced secondary ocular hypertension.

Conclusions:

  • Intravitreal triamcinolone acetonide is a potential treatment option for diffuse diabetic macular edema.
  • The treatment offers significant visual acuity gains but requires monitoring for ocular hypertension.