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Updated: Aug 25, 2026
Using Ex Vivo Upright Droplet Cultures of Whole Fetal Organs to Study Developmental Processes during Mouse Organogenesis
Published on: October 21, 2015
Application of the mouse exo utero development system in the study of developmental biology and teratology
Toshihisa Hatta1, Akihiro Matsumoto, Hiroki Otani
1Department of Anatomy, Faculty of Medicine, Shimane University, Izumo, Japan. thatta@med.shimane-u.ac.jp
Abstract:
The mouse exo utero development system is useful for analyzing the roles of molecules or interactions between tissues in the histogenesis of organs after the mid-gestational period. In the article presented here, we review the mouse exo utero development system and its specific modifications depending on different purposes as well as its advantages over and limitations compared to other systems in the study of developmental biology and teratology.
