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Peritoneal carcinomatosis in refractory seminoma
Takashige Abe1, Nobuo Shinohara, Tohru Harabayashi
1Departments of Urology Surgical Pathology, Hokkaido University School of Medicine Department of Urology, Sapporo City General Hospital, Sapporo, Japan. takataka@rf6.so-net.ne.jp
Abstract:
Intraperitoneal metastasis from a testicular germ cell tumor is very rare. We report a case in a 33-year-old man who was referred to Hokkaido University Hospital, Hokkaido, Japan, for further therapy for refractory seminoma. Physical examination revealed abdominal distension as a result of ascites, and cytology of the ascites showed seminoma cells. Although the ascites completely disappeared after treatment with a novel regimen of irinotecan-based chemotherapy, the patient had a recurrence of ascites and died of progressive disease 5 months after the start of the therapy.