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Cutaneous onchocercoma.

Jason F Okulicz1, Adam S Stibich, Dirk M Elston

  • 1Dermatology and Internal Medicine, Wilford Hall Medical Center, Lackland AFB, Texas, USA.

International Journal of Dermatology
|March 11, 2004
PubMed
Summary

Onchocerciasis, a chronic parasitic disease, presents with skin, eye, and body-wide symptoms. Ivermectin is the recommended treatment and preventative measure for this black fly-transmitted infection.

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Area of Science:

  • Parasitology
  • Tropical Medicine
  • Dermatology

Background:

  • Onchocerciasis, also known as river blindness, is a chronic multisystem disease endemic in Africa, Latin America, and Yemen.
  • It is caused by the nematode Onchocerca volvulus, transmitted via the bite of infected Simulium black flies.

Observation:

  • The disease manifests with significant dermatologic, ocular, and systemic symptoms.
  • Cutaneous manifestations include onchocercomas, which are palpable subcutaneous nodules containing adult worms.

Findings:

  • Imported cases of onchocerciasis have been documented in regions outside endemic areas, including the United States.
  • The antiparasitic drug ivermectin is highly effective.

Implications:

  • Ivermectin serves as the primary agent for both prophylaxis and treatment of active onchocerciasis.
  • Understanding transmission and clinical presentation is crucial for managing imported cases and potential spread.

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