Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extraction and validation of correlation lengths from interstitial velocity fields using diffusion-weighted MRI.

Kevin W Moser1, John G Georgiadis

  • 1Cardiovascular Imaging Technologies, LLC, Kansas City, MO, USA.

Magnetic Resonance Imaging
|March 11, 2004
PubMed
Summary

Quantitative Magnetic Resonance Imaging (q-space MRI) measures interstitial space dispersion. This study demonstrates q-space MRI can determine pore-scale flow characteristics in porous media.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accelerated, Physics-Inspired Inference of Skeletal Muscle Microstructure From Diffusion-Weighted MRI.

IEEE transactions on medical imaging·2024
Same author

Harmonic viscoelastic response of 3D histology-informed white matter model.

Molecular and cellular neurosciences·2022
Same author

Lattice Boltzmann method for simulation of diffusion magnetic resonance imaging physics in multiphase tissue models.

Physical review. E·2020
Same author

Sensitivity analysis of effective transverse shear viscoelastic and diffusional properties of myelinated white matter.

Physics in medicine and biology·2020
Same author

Immobilized RGD concentration and proteolytic degradation synergistically enhance vascular sprouting within hydrogel scaffolds of varying modulus.

Journal of biomaterials science. Polymer edition·2019
Same author

Global sensitivity analysis of skeletal muscle dMRI metrics: Effects of microstructural and pulse parameters.

Magnetic resonance in medicine·2019

Area of Science:

  • Physics
  • Biophysics
  • Materials Science

Background:

  • Magnetic Resonance Imaging (MRI) methods sensitive to molecular displacements, termed q-space MRI, offer a way to measure dispersion in complex interstitial spaces.
  • Understanding fluid flow and dispersion in porous media is crucial for various scientific and engineering applications.

Purpose of the Study:

  • To demonstrate the feasibility of using q-space MRI to measure the coherence length of the interstitial velocity field.
  • To extract an integral spatial scale characterizing the Eulerian velocity auto-correlation coefficient in fluid-saturated porous media.

Main Methods:

  • Performed pressure-driven flow experiments in a water-saturated packed bed phantom.
  • Measured the apparent dispersion coefficient's dependence on distance along the mean flow using pulsed-gradient stimulated-echo MRI with varying gradient pulse separation times.

Related Experiment Videos

  • Extracted integral length scale using a stochastic convective model and validated against phase contrast MRI measurements.

    • Main Results:

    • The integral length scale obtained via q-space MRI correlates well with the mean pore size of the phantom.
    • The method successfully quantifies interstitial morphology with resolution independent of voxel size.
    • Demonstrated agreement between q-space MRI derived length scale and direct pore-level MRI measurements.

    Conclusions:

    • Q-space MRI is a viable technique for characterizing interstitial flow and morphology in porous media.
    • The developed method provides a non-invasive way to quantify pore-scale transport properties.
    • This approach has significant potential for analyzing fluid-saturated porous materials.