Radiation-induced brachial plexopathy: review. Complication without a cure

Area of Science:

• Neurology
• Oncology
• Radiology

Background:

• Radiation therapy to the chest wall and axilla can lead to radiation-induced brachial plexopathy.
• This condition, particularly the chronic progressive form, presents significant challenges including pain and functional decline.
• Effective treatment remains a challenge for reconstructive peripheral nerve surgeons.

Purpose of the Study:

• To review the existing literature on radiation-induced brachial plexopathy.
• To summarize the current understanding of the pathophysiology, diagnosis, and treatment of this disorder.

Main Methods:

• Literature review of radiation-induced brachial plexopathy.

Main Results:

• Radiation-induced brachial plexopathy is an increasingly rare but challenging entity.
• Chronic pain and functional decline are significant patient concerns.
• Satisfactory treatment options are limited.

Conclusions:

• A comprehensive understanding of radiation-induced brachial plexopathy's pathophysiology, diagnosis, and treatment is crucial.
• Further research may be needed to identify more effective treatment strategies.
• This review provides a summary of current knowledge for clinicians and researchers.