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Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
GENES AND ENZYMES OF CAROTENOID BIOSYNTHESIS IN PLANTS
1Department of Microbiology, University of Maryland, College Park, MD 20742; e-mail: fc18@umail.umd.edu; eg37@umail.umd.edu
Annual Review of Plant Physiology and Plant Molecular Biology
|March 12, 2004
Summary
Carotenoid biosynthesis genes and enzymes are now well-identified. This review covers recent findings on their structure, function, metabolic engineering, and enzyme complex models for future research.
Area of Science:
- Plant Biology
- Biochemistry
- Molecular Biology
Background:
- Carotenoids are vital pigments in plant photosynthetic membranes.
- Recent advances have identified most genes for carotenoid biosynthesis.
- Understanding carotenoid pathways is crucial for plant science.
Purpose of the Study:
- To review recent findings on carotenoid biosynthesis genes and enzymes.
- To discuss key topics: precursor supply, metabolic engineering, and enzyme complexation.
- To present a model for carotenogenic enzyme complexes.
Main Methods:
- Literature review of recent scientific findings.
- Analysis of gene and enzyme structures and functions.
- Discussion of metabolic engineering strategies and enzyme compartmentation.
Main Results:
- Comprehensive identification of genes and enzymes in carotenoid biosynthesis.
- Insights into the source of isopentenyl pyrophosphate.
- Discussion on altering carotenoid content via metabolic engineering.
- Exploration of enzyme association and compartmentation.
Conclusions:
- Significant progress in understanding carotenoid biosynthesis pathways.
- Potential for metabolic engineering to modify plant carotenoid profiles.
- A proposed model for enzyme complexes to guide future research.
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