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Updated: Aug 25, 2026

Combining Single-molecule Manipulation and Imaging for the Study of Protein-DNA Interactions
Published on: August 27, 2014
Single-molecule spectroscopy
T Plakhotnik1, E A Donley, U P Wild
1Physical Chemistry Laboratory, Swiss Federal Institute of Technology, ETH-Zentrum, CH-8092, Zurich, Switzerland. taras@phys.chem.ethz.ch
Abstract:
Recent experimental and theoretical studies concerning single-molecule spectroscopy in solids are discussed. Pure quantum effects--such as photon bunching, antibunching, and spectral jumps--and more classical phenomena--such as near-field excitation, saturation, ac/dc Stark shifts, spectral diffusion, two-photon excitation, and customary spectroscopic analysis--are considered. The emphasis of this review is on physical results and their interpretation. This is preceded by a general introduction, where fundamentals of single-molecule spectroscopy are explained.
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