Related Experiment Video
Updated: Aug 25, 2026

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
Published on: October 2, 2020
Depression in chronic haemodialysed patients
Yong-Shing Chen1, San-Chiang Wu, Shiang-Yaw Wang
1Department of Psychiatry, Kaohsiung Municipal United Hospital, Kaohsiung, Taiwan.
Insights
Depression in chronic haemodialysis patients stems from psychosocial issues, not physical conditions. Addressing underlying disease and job status is key to improving mental well-being for these individuals.
Area of Science:
- Nephrology
- Psychiatry
- Public Health
Background:
- Chronic haemodialysis patients often experience clinical depression.
- Understanding the contributing factors to depression in this population is crucial for effective management.
Purpose of the Study:
- To investigate the prevalence and factors associated with clinical depression among chronic stable haemodialysed patients.
- To differentiate between physical and psychosocial contributors to depression in this cohort.
Main Methods:
- A cohort of 108 chronic stable haemodialysed patients were assessed for depression using The Taiwanese Depression Questionnaire (TDQ).
- Analysis focused on three dimensions: affective change, somatic complaint, and cognitive disturbance.
- Patients were categorized based on TDQ scores (cut-off > 19) and compared regarding underlying diseases, job status, nutrition, and toxin removal indexes.
Main Results:
- 33.4% of patients exhibited depression scores above the cut-off value.
- Diabetic patients and the elderly reported higher depression and somatic complaint scores, respectively.
- No significant differences in nutrition or toxin removal indexes were observed between depressed and non-depressed groups.
- Underlying disease and employment status were identified as major differentiating factors.
Conclusions:
- Depression in chronic haemodialysed patients is primarily linked to psychosocial factors rather than physical conditions.
- The findings highlight the need for targeted psychosocial support interventions for haemodialysis patients.
- Addressing underlying disease and employment challenges may mitigate depression in this patient group.
Abstract:
From April 2000 to April 2001, a total of 108 chronic stable haemodialysed patients (34 males aged 57.76 +/- 12.68 years under haemodialysis treatment for 31.41 +/- 24.71 months and 74 females aged 54.99 +/- 12.87 years under haemodialysis for 41.47 +/- 33.47 months) were studied for signs of clinical depression. Depression was measured by using 'The Taiwanese Depression Questionnaire (TDQ)'. After analysing various possible factors, we chose to study three dimensions: affective change, somatic complaint and cognitive disturbance. Thirty-six (33.4%) of the patients were found to have TDQ scores above 19; our cut-off value. Diabetic patients were also found to have higher depression scores and affective change scores than those without diabetes. The elderly suffered more from somatic complaints, and patients without jobs also tended to have higher depression scores. We compared the nutrition indexes and uraemic toxin removal indexes of those with higher depression scores (score > or =19) with those with normal scores (score <19), and we found no differences between the two groups. We found that an underlying disease and job status were the major differences found in the two groups. Therefore, our findings suggest that the depression found in our chronic haemodialysed patients was not a result of the physical conditions, but a result of psychosocial problems indicating a need for psychosocial support for these patients.
Related Concept Videos
Hemodialysis II: Procedure and Complications
Hemodialysis III: Nursing Management
Peritoneal Dialysis III: Nursing Management
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Dialysis
Chronic Kidney Disease III: Interprofessional Care