Telephonic back-up improves antibiotic compliance in acute tonsillitis/pharyngitis
A Molinos Urién1, V F Gil Guillén, D Orozco Beltrán
1Health Center El Campello, Alicante, Spain.
International Journal of Antimicrobial Agents
|March 12, 2004
Summary
Telephonic back-up significantly improved antibiotic treatment compliance for acute tonsillitis/pharyngitis patients. This intervention, when added to educational strategy, led to better adherence compared to education alone.
Area of Science:
- Clinical Medicine
- Infectious Diseases
- Public Health
Background:
- Antibiotic non-compliance is a significant issue in treating acute tonsillitis/pharyngitis.
- Educational strategies alone may not sufficiently improve patient adherence to antibiotic regimens.
- Optimizing antibiotic compliance is crucial for effective treatment and preventing resistance.
Purpose of the Study:
- To evaluate if telephonic back-up enhances antibiotic treatment compliance in acute tonsillitis/pharyngitis.
- To compare the effectiveness of educational strategy plus telephonic back-up against educational strategy alone.
- To quantify the clinical relevance of telephonic intervention on antibiotic adherence.
Main Methods:
- A randomized clinical trial involving 128 patients (64 per group).
- Intervention group received a telephone call on day four of antibiotic therapy.
- Compliance assessed by tablet count (80-110% defined as good compliance).
Main Results:
- Good compliance was significantly higher in the intervention group (78.3%) versus the control group (54.1%) (P=0.005).
- The intervention demonstrated an absolute risk reduction (ARR) of 24.2% and a relative risk reduction (RRR) of 52.7%.
- The number needed to treat (NNT) was calculated as 4.13, indicating a favorable clinical impact.
Conclusions:
- Telephonic back-up significantly improves antibiotic compliance when combined with educational strategies.
- This intervention offers a practical and effective method to enhance patient adherence in clinical practice.
- Implementing telephonic support is recommended for managing acute tonsillitis/pharyngitis treatment.
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