[Malignant tumors in the relatives of stomach cancer patients]

The author has studied the predisposition to gastric cancer in familiar probands of russian nationality suffering cancer of the stomach. An analysis of the gastric-cancer incidence among the groups of individuals of different degree of kinship of male and female probands indicates their various predisposition only to cancer of the stomach. Most frequently the affection was noted in the blood relations of female probands (mothers, sisters, and daughters). In this group familial gastric cancer was 5.2 times as frequent as the expected value. Familial gastric cancer among the male blood relations of these probands was no more frequent than among the whole population of russian nationality. Males and females--the blood relations of male probands were affected by gastric cancer approximately twice as frequently as the control subjects. The investigation conducted has shown that distant relations (2d and 3d degree of kinship) of all probands were affected by this kind of cancer at the average population level. Also, all kin groups did not show any high risk for other cancer forms.