Impact of delays to cardiac surgery after failed angioplasty and stenting
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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Mat Lotfi1, Karen Mackie, Vladimir Dzavik
1Division of Cardiology, Department of Medicine, University Health Network, University of Toronto, Toronto General Hospital, 200 Elizabeth Street, EN 12-238, Toronto, Ontario M5G 2C4, Canada.
Insights
Patients needing urgent coronary artery bypass graft (UCABG) surgery after percutaneous coronary intervention (PCI) face a significant risk of harm from delays. About one in four such patients are at increased risk if surgery is postponed.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Cardiac Surgery
Background:
- Patients undergoing percutaneous coronary intervention (PCI) at hospitals lacking on-site cardiac surgery face extended delays for urgent coronary artery bypass graft (UCABG) surgery.
- These delays can potentially increase the risk of adverse outcomes for patients requiring immediate surgical intervention.
Purpose of the Study:
- To assess the likelihood of harm in patients experiencing delays before undergoing urgent coronary artery bypass graft (UCABG) surgery after a failed percutaneous coronary intervention (PCI).
Main Methods:
- A retrospective chart review was conducted on patients who underwent UCABG following failed PCI.
- A predefined set of criteria, including hemodynamic instability, coronary perforation with effusion/tamponade, or severe ischemia, was used to identify patients at high risk of harm due to surgical delays.
Main Results:
- Out of 6,582 PCIs, 45 patients (0.7%) required UCABG. These patients more frequently had complex type C lesions and urgent indications.
- Among UCABG patients, 17.0% experienced myocardial infarction, and 2 patients died during hospitalization.
- Eleven patients (24.4%) met the criteria for high likelihood of harm with surgical delays. The absolute risk of harm was estimated at 1-2 per 1,000 PCIs.
Conclusions:
- A substantial proportion (approximately 24.4%) of patients referred for UCABG after PCI are at an elevated risk of harm if surgical delays occur.
- These findings highlight the critical need for timely surgical intervention in select PCI patients to mitigate potential adverse events.
Objectives:
This study was designed to determine the likelihood of harm in patients having additional delays before urgent coronary artery bypass graft (UCABG) surgery after percutaneous coronary intervention (PCI).
Background:
Patients who have PCI at hospitals without cardiac surgery have additional delays to surgery when UCABG is indicated.
Methods:
Detailed chart review was performed on all patients who had a failed PCI leading to UCABG at a large tertiary care hospital. A prespecified set of criteria (hemodynamic instability, coronary perforation with significant effusion or tamponade, or severe ischemia) was used to identify patients who would have an increased likelihood of harm with additional delays to surgery.
Results:
From 1996 to 2000, 6,582 PCIs were performed. There were 45 patients (0.7%) identified to have UCABG. The demographic characteristics of the UCABG patients were similar to the rest of the patients in the PCI database, except for significantly more type C lesions (45.3% vs. 25.0%, p < 0.001) and more urgent cases (66.6% vs. 49.8%, p = 0.03) in patients with UCABG. Myocardial infarction occurred in eight patients (17.0%) after UCABG, with a mean peak creatine kinase of 2,445 +/- 1,212 IU/l. Death during the index hospital admission occurred in two patients. Eleven of the 45 patients (24.4%) were identified by the prespecified criteria to be at high likelihood of harm with additional delays to surgery. The absolute risk of harm is approximately one to two patients per 1,000 PCIs.
Conclusions:
Approximately one in four patients referred for UCABG would be placed at increased risk of harm if delays to surgery were encountered.
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