Contemporary results of mitral valve repair for infective endocarditis

Bernard Iung1, Juliette Rousseau-Paziaud, Bertrand Cormier

  • 1Cardiology Department, Bichat Hospital AP-HP, 46 rue Henri Huchard, 75018 Paris, France. bernard.iung@bch.ap-hop-paris.fr

Abstract

Insights

Mitral valve repair (MVRep) is feasible for infective endocarditis, offering good long-term survival. While acute endocarditis patients face more follow-up events, both acute and healed cases show excellent late survival rates.

Area of Science:

  • Cardiovascular Surgery
  • Infective Diseases
  • Valvular Heart Disease

Background:

  • Mitral valve repair (MVRep) techniques have advanced, yet its application in endocarditis remains under-explored.
  • Limited data exists on the efficacy of MVRep for both acute and healed infective endocarditis.

Purpose of the Study:

  • To assess the feasibility of mitral valve repair (MVRep) in patients with infective endocarditis.
  • To evaluate the immediate and long-term outcomes of MVRep for acute and healed endocarditis.

Main Methods:

  • Retrospective analysis of 78 patients with mitral endocarditis (1990-1999).
  • 63 patients underwent mitral valve repair (MVRep), with 25 for acute and 38 for healed endocarditis.
  • Detailed analysis of repair techniques, early complications, and long-term event-free survival.

Main Results:

  • Mitral valve repair (MVRep) was feasible in 81% of patients, utilizing various techniques including annuloplasty, valve resection, and chordal repair.
  • Early complications included a 3.2% mortality rate and re-operations for mitral regurgitation and aortic endocarditis.
  • Seven-year event-free survival was 78%; hypertension and acute endocarditis were predictors of adverse events.

Conclusions:

  • Mitral valve repair (MVRep) is a feasible and effective treatment for infective endocarditis.
  • Patients with acute endocarditis experienced more follow-up events but demonstrated excellent long-term survival.
  • MVRep offers good results and excellent late survival for both acute and healed endocarditis.

Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...