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Updated: Aug 25, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Contemporary results of mitral valve repair for infective endocarditis
Bernard Iung1, Juliette Rousseau-Paziaud, Bertrand Cormier
1Cardiology Department, Bichat Hospital AP-HP, 46 rue Henri Huchard, 75018 Paris, France. bernard.iung@bch.ap-hop-paris.fr
Objectives:
We sought to evaluate the feasibility and immediate and late results of mitral valve repair (MVRep) for acute and healed endocarditis.
Background:
Improvements in techniques of MVRep have extended its feasibility in complex lesions, but experience with endocarditis is limited.
Methods:
Among 78 patients operated on for mitral endocarditis between 1990 and 1999, 63 underwent MVRep. The repair was performed for acute endocarditis in 25 patients (40%) at a median of 20 days after the onset of treatment and in 38 patients (60%) for healed endocarditis after a median of 11 months.
Results:
Repair of the mitral valve was feasible in 63 patients (81%). This repair involved annuloplasty in 61 patients (97%), valve resection in 49 (78%), shortening or transposition of chordae in 29 (46%), suture of perforation in 18 (29%), a pericardial patch in 12 (19%), and a partial mitral homograft in 7 (11%). Associated procedures were aortic valve replacement in 11 patients, bypass grafting in 3, and tricuspid repair in 2. Early complications were two deaths (3.2%), one re-operation for severe mitral regurgitation and one re-operation for subsequent aortic endocarditis. The seven-year rate of event-free survival was 78 +/- 6% in the global series. Multivariate predictors of event-free survival were hypertension (p < 0.006) and intervention for acute endocarditis (p < 0.026). Five-year survival rates were 96 +/- 4% after MVRep for acute endocarditis and 91 +/- 5% for healed endocarditis.
Conclusions:
Mitral valve repair is frequently feasible and gives good results in patients with infective endocarditis. Patients operated on for acute endocarditis experience more events during follow-up than those operated on after healed endocarditis but have excellent late survival.
Insights
Mitral valve repair (MVRep) is feasible for infective endocarditis, offering good long-term survival. While acute endocarditis patients face more follow-up events, both acute and healed cases show excellent late survival rates.
Area of Science:
- Cardiovascular Surgery
- Infective Diseases
- Valvular Heart Disease
Background:
- Mitral valve repair (MVRep) techniques have advanced, yet its application in endocarditis remains under-explored.
- Limited data exists on the efficacy of MVRep for both acute and healed infective endocarditis.
Purpose of the Study:
- To assess the feasibility of mitral valve repair (MVRep) in patients with infective endocarditis.
- To evaluate the immediate and long-term outcomes of MVRep for acute and healed endocarditis.
Main Methods:
- Retrospective analysis of 78 patients with mitral endocarditis (1990-1999).
- 63 patients underwent mitral valve repair (MVRep), with 25 for acute and 38 for healed endocarditis.
- Detailed analysis of repair techniques, early complications, and long-term event-free survival.
Main Results:
- Mitral valve repair (MVRep) was feasible in 81% of patients, utilizing various techniques including annuloplasty, valve resection, and chordal repair.
- Early complications included a 3.2% mortality rate and re-operations for mitral regurgitation and aortic endocarditis.
- Seven-year event-free survival was 78%; hypertension and acute endocarditis were predictors of adverse events.
Conclusions:
- Mitral valve repair (MVRep) is a feasible and effective treatment for infective endocarditis.
- Patients with acute endocarditis experienced more follow-up events but demonstrated excellent long-term survival.
- MVRep offers good results and excellent late survival for both acute and healed endocarditis.
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