Related Experiment Videos
Pregnancy and renal transplantation
O Başaran1, R Emiroğlu, S Seçme
1Başkent University Faculty of Medicine, Departments of General Surgery and Transplantation Center, 1. Cadde no. 77 Bahcelievler, Ankara 06490, Turkey.
Transplantation Proceedings
|March 12, 2004
Summary
Successful pregnancy is achievable for women with chronic renal failure post-kidney transplant. Good graft function ensures maternal safety, though fetal complications like intrauterine growth retardation and preeclampsia may occur.
Area of Science:
- Nephrology
- Reproductive Endocrinology
- Transplant Surgery
Background:
- Chronic renal failure causes infertility due to hormonal imbalances.
- Renal transplantation often restores endocrine function and fertility.
- Evaluating pregnancy outcomes in renal transplant recipients is crucial.
Purpose of the Study:
- To assess pregnancy outcomes in renal transplant recipients.
- To evaluate maternal and fetal complications.
- To determine the impact of pregnancy on renal graft function.
Main Methods:
- Retrospective analysis of eight pregnancies in eight renal transplant recipients.
- Data collected on pre- and post-pregnancy renal function, gestation outcomes, and complications.
- Follow-up period of 2 years post-delivery.
Main Results:
- Eight planned pregnancies occurred at a mean of 3.6 years post-transplant.
- Seven deliveries resulted in live births with no congenital anomalies or postpartum issues.
- Pregnancy did not negatively impact renal function, proteinuria, or rejection rates.
- Fetal complications included intrauterine growth retardation, preterm delivery, preeclampsia, and oligohydramnios.
Conclusions:
- Successful pregnancy is possible in renal transplant recipients with good graft function.
- Pregnancy does not compromise graft function or patient survival in selected cases.
- Fetal complications necessitate careful monitoring during pregnancy post-transplant.