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Updated: Aug 25, 2026

Investigations on the Ga(III) Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue
Published on: August 17, 2016
Biological studies of radiolabeled glucose analogues iodinated in positions 3, 4 or 6
Pascale Perret1, Catherine Ghezzi, Lionel Ogier
1Radiopharmaceutiques Biocliniques, INSERM E03 40, Université Joseph Fourier, 38000 Grenoble, France.
Abstract:
The aim of this study was to assess the biological behavior of new radiolabeled glucose analogues proposed as tracers of glucose uptake in vivo and iodinated in position 3, 4, or 6. Biological results obtained in vitro on adipocytes and erythrocytes and in vivo in mice were compared to those obtained with the gold-standard tracer of glucose uptake, 2-deoxy-D-glucose. None of these molecules had the same biological behavior than 2-deoxy-D-glucose. Therefore, these compounds cannot be considered as tracers of glucose uptake.
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