Effects of tonsillectomy and adenoidectomy on hemoglobin and iron metabolism

Hans H Elverland1, Gunbjørn Aasand, Harald Miljeteig

  • 1Department of Otorhinolaryngology, University Hospital of Northern Norway, N-9038 Tromso, Norway. helverla@online.no

Insights

Tonsillectomy and adenoidectomy significantly improved hemoglobin levels and iron metabolism in children, reducing anemia prevalence. Iron deficiency was common before surgery.

Area of Science:

  • Pediatric Otolaryngology
  • Hematology
  • Nutritional Science

Background:

  • Recurrent tonsillitis and upper airway obstruction often necessitate surgical intervention in children.
  • Anemia and iron deficiency are prevalent conditions that can affect children's health and development.

Purpose of the Study:

  • To evaluate the impact of adenoidectomy, tonsillectomy, or combined procedures on hemoglobin concentration and iron metabolism in pediatric patients.
  • To assess changes in iron status markers following surgical treatment for tonsillitis or airway obstruction.

Main Methods:

  • Prospective analysis of venous blood samples from children undergoing tonsillectomy and/or adenoidectomy.
  • Measurement of hemoglobin, serum ferritin, and erythrocyte protoporphyrin IX at baseline and 6 months post-surgery in patients without iron supplementation.

Main Results:

  • A median increase of 1.4g/dL in hemoglobin concentration was observed post-surgery.
  • Significant reduction in erythrocyte protoporphyrin IX levels, indicating improved iron utilization.
  • Preoperative anemia prevalence of 56.3% decreased to 7.71% at follow-up; serum ferritin levels remained low.

Conclusions:

  • Tonsillectomy and adenoidectomy demonstrate a positive effect on hemoglobin levels and iron metabolism in children.
  • Surgical intervention for tonsillitis or airway obstruction can ameliorate anemia.
  • Iron deficiency remains a common comorbidity in this pediatric population.
Abstract

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