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Published on: March 14, 2017
Effects of tonsillectomy and adenoidectomy on hemoglobin and iron metabolism
Hans H Elverland1, Gunbjørn Aasand, Harald Miljeteig
1Department of Otorhinolaryngology, University Hospital of Northern Norway, N-9038 Tromso, Norway. helverla@online.no
Insights
Tonsillectomy and adenoidectomy significantly improved hemoglobin levels and iron metabolism in children, reducing anemia prevalence. Iron deficiency was common before surgery.
Area of Science:
- Pediatric Otolaryngology
- Hematology
- Nutritional Science
Background:
- Recurrent tonsillitis and upper airway obstruction often necessitate surgical intervention in children.
- Anemia and iron deficiency are prevalent conditions that can affect children's health and development.
Purpose of the Study:
- To evaluate the impact of adenoidectomy, tonsillectomy, or combined procedures on hemoglobin concentration and iron metabolism in pediatric patients.
- To assess changes in iron status markers following surgical treatment for tonsillitis or airway obstruction.
Main Methods:
- Prospective analysis of venous blood samples from children undergoing tonsillectomy and/or adenoidectomy.
- Measurement of hemoglobin, serum ferritin, and erythrocyte protoporphyrin IX at baseline and 6 months post-surgery in patients without iron supplementation.
Main Results:
- A median increase of 1.4g/dL in hemoglobin concentration was observed post-surgery.
- Significant reduction in erythrocyte protoporphyrin IX levels, indicating improved iron utilization.
- Preoperative anemia prevalence of 56.3% decreased to 7.71% at follow-up; serum ferritin levels remained low.
Conclusions:
- Tonsillectomy and adenoidectomy demonstrate a positive effect on hemoglobin levels and iron metabolism in children.
- Surgical intervention for tonsillitis or airway obstruction can ameliorate anemia.
- Iron deficiency remains a common comorbidity in this pediatric population.
Objectives:
To investigate a possible effect of adenoidectomy, tonsillectomy, or both operations combined in children on hemoglobin concentration and iron metabolism.
Methods:
Children eligible for surgery due to recurrent tonsillitis or upper airway obstruction had a venous blood sample drawn at the time of the operation and 6 months later. One hundred and three preoperative and 91 blood samples at follow-up from patients not given iron supplementation were available for analysis of hemoglobin concentration, serum-ferritin and protoporphyrin-IX in erythrocytes.
Results:
A 1.4g/dl median increase in hemoglobin concentration during the observation period was associated with a significant reduction of protoporphyrin-IX, while serum-ferritin remained unchanged and low. A preoperative prevalence of anemia of 56.3% was reduced to 7.71%. All combinations of normal and pathological values of serum-ferritin and protoporphyrin-IX were found in anemic and non-anemic patients.
Conclusions:
A beneficial effect of tonsillectomy and adenoidectomy on hemoglobin and iron metabolism was demonstrated. Iron deficiency was common.
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