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Related Experiment Videos

Real-World Outcomes of Once-Daily Risperidone Dosing.

Sanjay Gupta1, Sadiq Al-Samarrai, Prakash S. Masand

  • 1Department of Psychiatry, Olean General Hospital, Olean; the Department of Psychiatry, SUNY Upstate Medical University at Syracuse, Syracuse; the Department of Psychiatry, University of Buffalo, Buffalo; and Cattaraugus County Continuing Day Treatment Program, Olean, N.Y.

Primary Care Companion to the Journal of Clinical Psychiatry
|March 12, 2004
PubMed
Summary
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Once-daily risperidone effectively controlled psychiatric disorders in most patients over 18 months. This antipsychotic medication was well tolerated, enhancing compliance without increased side effects.

Area of Science:

  • Psychiatry
  • Pharmacology

Background:

  • Risperidone is an established antipsychotic with proven efficacy.
  • Recent findings suggest its effectiveness and safety in a once-daily regimen.

Purpose of the Study:

  • To assess the efficacy and safety of once-daily risperidone.
  • To evaluate its tolerability and impact on compliance in patients with diverse psychiatric disorders.

Main Methods:

  • Retrospective study of 27 patients in a community day treatment program.
  • Patients received once-daily risperidone for a mean of over 18 months.
  • Included diagnoses: schizophrenia, schizoaffective disorder, bipolar disorder, major depression with psychosis, PTSD.

Main Results:

  • Once-daily risperidone dosages (1-6 mg/day) controlled disorders in most patients.

Related Experiment Videos

  • The regimen was well tolerated, with no increase in antipsychotic-related side effects.
  • Enhanced patient compliance was observed.

    • Conclusions:

    • Once-daily risperidone is well tolerated.
    • No patients required antiparkinsonian medications, even at higher dosages.
    • Supports the use of once-daily risperidone for various psychiatric conditions.