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Updated: Aug 25, 2026
Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
[Flavonoids from rhizome of Alpinia tonkinensis]
Jian Zhang1, Qing-hai Guo, Ling-yi Kong
1Department of Natural Medicinal Chemistry, China Pharmaceutical University, Jiangsu, Nanjing 210038.
Objective:
To find out the bioactive principles of Alpinia tonkinensis, by investigating its chemical constituents.
Method:
It was extracted with MeOH, distributed by different solvents, and isolated via column chromatography on silica gel.
Result:
Six compounds were elucidated through spectral analysis, which were as follows: 4',7-dimethylkaempferol(I), 5-hydroxy-3',4',7-trimethoxyflavanone(II), kumatakenin(III), 4',5,7-trimethoxyflavonol(IV), ombuine(V), and kaempferol(VI).
Conclusion:
Six flavonoids were isolated from this plant for the first time, and so were four compounds from genus Alpinia.
