Related Experiment Video
Updated: Aug 25, 2026
Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue
Published on: January 6, 2012
[Effect of TCTS on experimental endometriosis of rats]
Min Hong1, Yong-qing Hua, Li Yu
1National Standard Lab of Pharmacology for Chinese Materia Medica, Nanjing 210029, Jiangsu, China.
Objective:
To study the effect of TCTS on endometriosis rats.
Method:
On the model of surgical induced rat endometriosis, weight and pathological changes of endometrial transplant and serum hormones were observed.
Result:
Weight of endometrial transplants was reduced by TCTS 11.2 g.kg-1 and 22.5 g.kg-1 and transplants of TCTS treated rat showed poorly developed epithelium, thinner stroma, fewer stromal cells and glands. At the same time elevated serum E2, FSH and LH were reduced by TCTS.
Conclusion:
TCTS can inhibit the growth of endometrial transplants, which is related with serum hormone, especially E2.
