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Published on: June 11, 2012
Life with continuous subcutaneous insulin infusion (CSII) therapy: child and parental perspectives and predictors of
A K Maniatis1, S R Toig, G J Klingensmith
1The Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, 80262, USA.
Insights
Needle fear in pediatric patients on continuous subcutaneous insulin infusion (CSII) therapy is linked to poorer metabolic control. Parental involvement and anxiety generally remained stable or decreased during CSII therapy.
Area of Science:
- Pediatric Endocrinology
- Metabolic Disorders
- Diabetes Management
Background:
- Continuous subcutaneous insulin infusion (CSII) therapy is a common treatment for pediatric diabetes.
- Evaluating CSII therapy's impact on metabolic control and parental factors is crucial for optimizing patient care.
Purpose of the Study:
- To assess metabolic control in pediatric patients using CSII therapy.
- To identify reasons for initiating CSII and daily management challenges, including needle fear.
- To evaluate changes in parental involvement and anxiety after initiating CSII therapy.
Main Methods:
- The study included 52 pediatric patients (aged 7.6-23.6 years) from a diabetes clinic.
- Management issues analyzed included diet, exercise, home blood glucose monitoring (HBGM) frequency, and needle fear.
- Metabolic control was assessed by HbA1c changes and final HbA1c levels.
Main Results:
- Needle fear was present in over a quarter of subjects (26.9%) and predicted poorer metabolic control (p=0.03).
- Most patients initiated CSII for better control, to avoid injections, and for flexibility.
- Home blood glucose monitoring (HBGM) frequency increased significantly on CSII (p=0.02).
Conclusions:
- Needle fear is a significant predictor of suboptimal metabolic control in pediatric CSII therapy.
- CSII therapy did not lead to increased parental involvement or anxiety, even with poorer metabolic control.
Objective:
The purpose of this study was twofold (i): to evaluate metabolic control in patients receiving CSII therapy in a routine pediatric diabetes clinic by describing reasons for initiating therapy and daily management issues, including needle fear; and (ii) to assess the change in parental involvement and anxiety once their child initiated CSII therapy.
Research Design And Methods:
The study included 52 subjects (aged 7.6-23.6 yr) from a general pediatric diabetes clinic. Management issues were defined as diet, exercise, home blood glucose monitoring (HBGM) frequency, and self/staff assessment of needle fear. Characteristics were analyzed both according to a 0.5% change in HbA1c status (decreased vs. stable vs. increased) compared with pre-CSII therapy, and final HbA1c achieved (< or = 8.1 vs. > 8.1%).
Results:
The primary recommendation source for CSII use was most often the physician/diabetes team (48.1%), followed by a combination of the former with a personal referral source (32.7%). The most common reason (71.2%) for CSII initiation was a combination of wanting to achieve better metabolic control, dislike of insulin injections, and/or increased flexibility in daily living. Over one-quarter (26.9%) of subjects were identified as being needle-fearful, and this characteristic was predictive of final metabolic control (3/25 subjects = 8.1% vs. 11/27 subjects > 8.1%, p = 0.03). On CSII therapy, dietary carbohydrate consistency was highly variable, and most subjects (65.3%) exclusively used an insulin to carbohydrate ratio for insulin bolus dosage calculation. The most common adjustment strategy (63.5%) for exercise was a combination of decreasing the insulin basal rate, disconnecting the pump, and/or eating extra carbohydrates. For the total cohort, the frequency of HBGM significantly increased on CSII therapy (4.31-4.85 tests/day, p = 0.02). Females did not have a significant change in HBGM frequency, while the youngest subjects had the highest HBGM frequency. Parental involvement and anxiety primarily stayed the same or decreased, regardless of the child's age (< or = 18 vs. > 18 yr) or metabolic control.
Conclusions:
Analyses of the various characteristics identified only needle fearfulness as being predictive of poor metabolic control. Interestingly, poor control with CSII therapy did not result in a significant increase in parental involvement and/or anxiety.
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