Drug pathways: moving beyond single gene pharmacogenetics

Integrating Somatic and Germline Pharmacogenomics for Therapeutic Decisions in Precision Oncology.

JCO precision oncology·2026

Propranolol metabolite and enantiomers affect colorectal cancer development by inhibiting MAPK pathway and downregulating PD-1 expression.

International immunopharmacology·2025

A two-stage genome-wide association study to identify novel genetic loci associated with irAEs in lung cancer patients receiving PD-1/PD-L1 inhibitors.

Cancer letters·2025

Advancing the science of genomic learning healthcare systems.

Learning health systems·2025

Causal effects of immune cells on the efficacy and adverse drug reactions of platinum drugs.

Acta biochimica et biophysica Sinica·2025

Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study.

Journal for immunotherapy of cancer·2024

Adherence to international pharmacogenomic recommendations in pediatric cancer care: a cohort analysis embedded within the MARVEL-PIC randomized trial.

Pharmacogenomics·2026

Closely similar tacrolimus morning troughs and graft function across the recipients' common ABCB1 polymorphisms (c.2677G>T/A, c.1236C>T, c.3435C>T) early after renal transplantation.

Pharmacogenomics·2026

Pharmacogenomics for stratified antidepressant treatment in major depressive disorder: evidence, limits and a roadmap for clinical use.

Pharmacogenomics·2026

Guidance from an informed public on collecting and sharing PGx test results for major depressive disorder: "It's no different from your blood type".

Pharmacogenomics·2026

Optimizing pharmacogenomics workflows: a qualitative evaluation of clinical service delivery models.

Pharmacogenomics·2026

Combinations of single gene predictors with AI-driven polygenic precision therapies in cardiovascular diseases.

Pharmacogenomics·2026

Exploring the Distinct Regulatory Actions and Molecular Pathways of Coptisine Through Network Pharmacology: Insights Into Its Influence on Platelet Activation and Thrombus Development.

Food science & nutrition·2026

Effect of Betahistine on Daytime Sedation and Metabolic Parameters in Patients with Schizophrenia on Second-generation Antipsychotics.

Indian journal of psychological medicine·2026

Adult dual and polytobacco use in the United States: Findings from the 2021-2023 National Survey on Drug Use and Health.

Preventive medicine reports·2026

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Following Orthopedic Shoulder Surgery: A Comparative Analysis.

Cureus·2026

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Are Associated With Reduced Early but Increased Chronic Postoperative Opioid Use After Shoulder Surgery.

Cureus·2026

Simvastatin modulates sleep-wake behavior and locomotor activity in a dose-dependent manner in Drosophila.

Frontiers in pharmacology·2026

Related Experiment Videos

Drug pathways: moving beyond single gene pharmacogenetics

Related Concept Videos

Integrating Somatic and Germline Pharmacogenomics for Therapeutic Decisions in Precision Oncology.

Propranolol metabolite and enantiomers affect colorectal cancer development by inhibiting MAPK pathway and downregulating PD-1 expression.

A two-stage genome-wide association study to identify novel genetic loci associated with irAEs in lung cancer patients receiving PD-1/PD-L1 inhibitors.

Advancing the science of genomic learning healthcare systems.

Causal effects of immune cells on the efficacy and adverse drug reactions of platinum drugs.

Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study.

Adherence to international pharmacogenomic recommendations in pediatric cancer care: a cohort analysis embedded within the MARVEL-PIC randomized trial.

Closely similar tacrolimus morning troughs and graft function across the recipients' common ABCB1 polymorphisms (c.2677G>T/A, c.1236C>T, c.3435C>T) early after renal transplantation.

Pharmacogenomics for stratified antidepressant treatment in major depressive disorder: evidence, limits and a roadmap for clinical use.

Guidance from an informed public on collecting and sharing PGx test results for major depressive disorder: "It's no different from your blood type".

Optimizing pharmacogenomics workflows: a qualitative evaluation of clinical service delivery models.

Combinations of single gene predictors with AI-driven polygenic precision therapies in cardiovascular diseases.

Exploring the Distinct Regulatory Actions and Molecular Pathways of Coptisine Through Network Pharmacology: Insights Into Its Influence on Platelet Activation and Thrombus Development.

Effect of Betahistine on Daytime Sedation and Metabolic Parameters in Patients with Schizophrenia on Second-generation Antipsychotics.

Adult dual and polytobacco use in the United States: Findings from the 2021-2023 National Survey on Drug Use and Health.

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Versus Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists Following Orthopedic Shoulder Surgery: A Comparative Analysis.

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors Are Associated With Reduced Early but Increased Chronic Postoperative Opioid Use After Shoulder Surgery.

Simvastatin modulates sleep-wake behavior and locomotor activity in a dose-dependent manner in Drosophila.

Related Experiment Videos

Drug pathways: moving beyond single gene pharmacogenetics

Related Concept Videos

Related Articles