Solitary retinal astrocytoma in a dog

An intraocular mass from a 13-year old Husky-mix dog was diagnosed as retinal astrocytoma. The mass arose from the ganglion layer of the retina and occupied 50% of the vitreous space. The mass was immunoreactive for neuron-specific enolase, S-100, vimentin, and glial fibrillary acidic protein. The neoplasm had characteristics similar to solitary retinal astrocytomas of humans but lacked the marked vascularity.