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A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
Published on: January 11, 2018
[Expression of testosterone in the rapid growing rat condylar cartilage and the expression changes after the function
Xiao-bin Li1, Kai-yun Chen, Zheng Zhou
1Dept. of Orthodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
Objective:
To investigate the expressions of Testosterone in the condylar cartilage of rapid growing rats.
Methods:
The mimic functional appliances were used in experiment groups and rats were killed after 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks. Immunohistochemical technique was used to detect the expression of T.
Results:
T was expressed throughout the condylar cartilage. The Highest expressions were in mature layers of both experiment and control groups. Along with the maturation, the expressions of T in the condylar cartilage were changed respectively, and the immunostain levels in the mature layer of experiment groups 2 and 3 weeks were higher than those of control groups (P < 0.05).
Conclusion:
1. T is a member of cartilage growth and development control system. 2. The orthopedic mechanism of functional appliance may be conducted by T.
