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Hemolysis, hemorrhage, headache, and hidden abortion: imaging findings in antiphospholipid syndrome
Andreas H Mahnken1, Vincent M Brandenburg, Rolf D Frank
1Department of Diagnostic Radiology, University Hospital, University of Technology, Pauwelsstrasse 30, 52057 Aachen, Germany. mahnken@rad.rwth-aachen.de
Abstract:
Antiphospholipid antibodies are associated with arterial and venous thromboses, recurrent pregnancy loss, and organ infarction. Any vascular region can be affected. We present a 20-year-old woman suffering from secondary antiphospholipid syndrome with a unique combination of multifocal venous thromboses, pulmonary embolism, spontaneous abortion, and splenic infarction. Diversity of clinical symptoms and diagnostic imaging modalities are discussed with emphasis on cross-sectional imaging. The syndrome should be suspected in patients with thromboses and organ infarctions of otherwise undetermined etiology.
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