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Intravenous methotrexate for treatment of interstitial pregnancy: a case report
Anthony Al-Khan1, Roger Jones, Donald Fricchione
1Department of Obstetrics, Gynecology and Women's Health, New Jersey Medical School, and Columbus Hospital, Newark, New Jersey 07101-1709, USA.
Background:
Ectopic pregnancy is the leading cause of first-trimester maternal death, accounting for 9% of pregnancy-related deaths. Interstitial (cornual) pregnancies represent 6% of all ectopics but account for a disproportionately higher mortality rate. Surgical management has been the treatment of choice for interstitial pregnancies. A very limited number of articles pre have explored the use of intravenous methotrexate to treat cornual pregnancy as a possible conservative first-line therapy in selected, hemodynamically stable patients.
Case:
A patient with a confirmed interstitial pregnancy was treated with intravenous methotrexate. The patient's beta-hCG levels decreased to zero within 9 weeks.
Conclusion:
Intravenous methotrexate was used successfully in the treatment of an interstitial pregnancy without complications.
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