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Updated: Aug 25, 2026
Shallow Water (Paddling) Variants of Water Maze Tests in Mice
Published on: June 3, 2013
Swim posture of mice does not affect performance in the water maze
L Enthoven1, S Dalm, E R de Kloet
1Division of Medical Pharmacology, Leiden/Amsterdam Center for Drug Research and Leiden University Medical Center, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands. l.enthoven@lacdr.leidenuniv.nl
Abstract:
We quantified swim postures of mice in relation to their cognitive performance. After training in a water maze, young (5-6 months) and aged (14-16 months) female apolipoprotein E-knockout (apoE0/0) mice and wild type controls were video taped while swimming. Subsequently, angles of body points with the water surface were calculated. Mice with a more horizontal swim posture (young and aged apoE0/0, aged wild type mice) also showed an increased body weight. However, swim posture was not related to cognitive performance.
