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Ionic perylenetetracarboxdiimides: highly fluorescent and water-soluble dyes for biolabeling

Jianqiang Qu1, Christopher Kohl, Mark Pottek

  • 1Max-Planck-Institut für Polymerforschung, Ackermannweg 10, 55128 Mainz, Germany.

Angewandte Chemie (International Ed. in English)
|March 17, 2004
PubMed
Abstract

No abstract available in PubMed .

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...