[The calcified ascending aorta in aortocoronary bypass]
Dusko Nezić1, Aleksandar Knezević, Milan Cirković
1Institut za kardiovaskularne bolesti Dedinje, Beograd. nezic@EUnet.yu
Insights
Surgical modifications for coronary artery bypass grafting in patients with heavily calcified ascending aorta reduced stroke and systemic embolization risks. These innovative techniques improved patient outcomes, avoiding complications like atheroembolism.
Area of Science:
- Cardiovascular Surgery
- Atherosclerosis Research
- Vascular Medicine
Context:
- Heavily calcified ascending aorta poses significant risks during open-heart surgery, including aortic wall damage and fatal atheroembolization.
- Standard cannulation and clamping techniques can lead to embolization of atheromatous debris to critical organs like the brain and myocardium.
- Coronary artery bypass grafting (CABG) in patients with severe atheroma requires specialized approaches to mitigate these risks.
Purpose:
- To evaluate the safety and efficacy of modified surgical techniques for CABG in patients with severely calcified ascending aorta.
- To assess the potential of these modifications in reducing the incidence of stroke and systemic embolization.
- To present alternative cannulation and myocardial revascularization strategies in high-risk patients.
Summary:
- Eleven patients with severe atheromatous ascending aorta underwent CABG using modified techniques between June 1998 and June 2000.
- Approaches included aortic arch cannulation, femoral artery cannulation, profound hypothermia with circulatory arrest, and off-pump or beating-heart procedures.
- Postoperative outcomes were uneventful, with no instances of atheroembolism to peripheral organs or extremities.
Impact:
- Modified surgical strategies can significantly decrease the prevalence of stroke and systemic embolization in CABG patients with heavily calcified aortas.
- These techniques offer a safer alternative for high-risk cardiovascular surgery patients.
- The study highlights the importance of adapting standard cardiosurgical techniques to individual patient pathology for improved safety and outcomes.
Abstract:
Heavily calcified ascending aorta significantly increased morbidity and lethality during open-heart surgery. Cannulation and clamping (partial or total) of severely atherosclerotic ascending aorta can easily cause damage and rupture of aortic wall, with consequential distal (often fatal) embolization with atheromatous debris (brain, myocardium). From June 1998. until June 2000, 11 of 2,136 (0.5%) patients who underwent coronary artery bypass grafting were with the severe atheromatous ascending aorta. The site of cannulation was in the aortic arch in three patients (aorta was occluded with Foley catheter in one case, and single clamp technique was used in the other two cases). The femoral artery was the cannulation site in other five cases. Profound hypothermia, ventricular fibrillation, and circulatory arrest, with no cross-clamping or cardioplegia, were used in three patients. Two patients were operated on with extracorporeal circulation, one in normothermia, on the beating heart, the other in moderate hypothermia, on fibrillating heart. In three patients myocardial revascularization was performed on the beating heart, in normothermia, without extracorporeal circulation. Postoperative course was uneventful in all 11 patients. Neither atheroembolism in the peripheral organs, nor atheroembolism of the extremities occurred. The proposed surgical approaches have the potential to reduce the prevalence of stroke and systemic embolization associated with coronary artery bypass grafting in patients with heavily calcified ascending aorta. This result was achieved due to the applied modifications of standard cardiosurgical technique.
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