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Updated: Aug 14, 2026

Quantitative Autonomic Testing
Published on: July 19, 2011
[Orthostatic hypotension: an unusual manifestation of pheochromocytoma]
Rodrigo Tagle1, Pamela Acosta, Gloria Valdés
1Departamento de Nefrología, Pontificia Universidad Católica de Chile, Marcoleta 354, Santiago. rtagle@med.puc.cl
Abstract:
Pheochromocytoma, though an uncommon cause of hypertension, can be a lethal condition. Because of this it is mandatory to diagnose it or rule it out in presence of suggestive symptoms. Typical symptoms are palpitations, sweating, severe headaches and hypertension. However, there are other suggestive symptoms of this dangerous endocrine entity, one of which is the orthostatic hypotension. We report the case of a 65 years old female patient with long standing hypertension in whom the pheochromocytoma was suspected after episodes of orthostatic hypotension. Although this manifestation was described almost fifty years ago, its frequency and pathophysiology has not yet been well established and fully elucidated. Moreover, it has meaningful implications in relation to preoperatory management and the timing of surgery.
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