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Related Experiment Videos

Urticaria and angioedema: a practical approach.

Barbara A Muller1

  • 1University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa 52242-1081, USA.

American Family Physician
|March 17, 2004
PubMed
Summary

Urticaria and angioedema affect many people. Diagnosis requires a thorough approach, and treatment involves avoiding triggers and using various medications for symptom relief.

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Area of Science:

  • Dermatology
  • Allergy and Immunology

Background:

  • Urticaria (pruritic wheals) and angioedema (swelling) affect up to 25% of the US population.
  • These conditions result from vasoactive mediators released from mast cells and basophils.
  • Diagnosis can be difficult, particularly with chronic or treatment-resistant symptoms.

Purpose of the Study:

  • To outline diagnostic and therapeutic strategies for urticaria and angioedema.
  • To emphasize the importance of a methodical approach in challenging cases.
  • To provide an overview of current treatment options.

Main Methods:

  • Review of medical literature on urticaria and angioedema.
  • Emphasis on thorough medical history and physical examination.
  • Discussion of a stepwise approach to diagnosis and therapy.

Main Results:

  • Acute urticaria is generally benign and self-limited.
  • Chronic urticaria may indicate concurrent serious medical illness.
  • Effective management involves trigger avoidance and pharmacotherapy.

Conclusions:

  • A comprehensive diagnostic process is essential for urticaria and angioedema.
  • Treatment strategies include trigger avoidance, corticosteroids, antihistamines, and other agents.
  • Consultation for advanced therapies may be needed for refractory cases.

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