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Updated: Aug 25, 2026

Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures
10:01

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Published on: March 12, 2018

Door-to-Balloon Delays with PCI in Acute Myocardial Infarction

Daniel R. Guerra1, C. Michael Gibson

  • 1TIMI Data Coordinating Center and Angiographic Core Laboratory, 350 Longwood Avenue, First Floor, Boston, MA 02115, USA. mgibson@perfuse.org

Current Treatment Options in Cardiovascular Medicine
|March 17, 2004
PubMed

Insights

Reducing door-to-balloon time is critical for improving outcomes in acute myocardial infarction (AMI) patients undergoing primary percutaneous transluminal coronary angioplasty (PTCA). Faster revascularization maximizes the benefits of PTCA and reduces mortality risks.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Emergency Medicine

Background:

  • Timely revascularization is key in acute myocardial infarction (AMI) treatment.
  • Primary percutaneous transluminal coronary angioplasty (PTCA) offers superior outcomes compared to thrombolysis.
  • Primary PTCA can lead to longer door-to-balloon times.

Purpose of the Study:

  • To emphasize the critical importance of minimizing door-to-balloon time in AMI treatment.
  • To highlight the negative impact of delays on primary PTCA efficacy.
  • To advocate for streamlined protocols to improve patient outcomes.

Main Methods:

  • Review of clinical data and established treatment protocols for AMI.
  • Analysis of the relationship between door-to-balloon time and patient outcomes.
  • Emphasis on institutional performance assessment.

Main Results:

  • Increased door-to-balloon time diminishes the benefits of primary PTCA.
  • Shorter delays correlate with improved infarct-related artery patency and reduced mortality.
  • Protocols and performance monitoring are essential for reducing delays.

Conclusions:

  • Institutions offering PTCA must prioritize reducing door-to-balloon times.
  • Implementing established protocols and continuous performance assessment are vital.
  • Minimizing delays enhances the effectiveness of primary PTCA in AMI management.

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