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Related Experiment Videos

[Cardiopulmonary exercise capacity increases after interventional ASD-closure].

M Weber1, T Neumann, M Rau

  • 1Kerckhoff-Klinik, Abteilung für Kardiologie, Benekestrasse 2-8, 61231 Bad Nauheim, Germany. Michael.Weber@kerckhoff.med.uni-giessen.de

Zeitschrift Fur Kardiologie
|March 17, 2004
PubMed
Summary

Transcatheter closure of atrial septal defects (ASD) does not immediately improve exercise capacity. However, significant improvements in exercise capacity are observed 12 months after ASD closure in most patients.

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Area of Science:

  • Cardiology
  • Pulmonology
  • Exercise Physiology

Context:

  • Secundum-type atrial septal defects (ASD) often lead to reduced exercise tolerance.
  • Current guidelines recommend ASD closure for symptomatic patients or those with significant shunts (Qp/Qs > 1.5).
  • Objective data on cardiopulmonary exercise capacity post-ASD closure are limited.

Purpose:

  • To evaluate exercise capacity using ergospirometry in adult patients with ASD.
  • To assess changes in exercise capacity at baseline and long-term after transcatheter ASD closure.

Summary:

  • Thirty adult ASD patients underwent exercise testing before and after transcatheter closure.
  • No significant improvement in VO(2) peak, VO(2)-AT, or maximal workload was noted at 1-6 months post-closure.

Related Experiment Videos

  • A significant increase in VO(2) peak, VO(2)-AT, and maximal workload was observed at 12 months post-closure.

    • Impact:

    • Late improvement in exercise capacity (12 months) after ASD closure is significant.
    • The benefits are observed across diverse patient demographics, including varying age, gender, and defect size.
    • This study provides crucial long-term objective data on exercise capacity recovery following transcatheter ASD closure.