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Improved application of Lidocaine/Prilocaine cream in children. A randomized and prospectively controlled study of

L N Gad1, K S Olsen, A B Lysgaard

  • 1Department of Anaesthesia and Intensive Care, Glostrup University Hospital, Copenhagen, Denmark.

Acta Anaesthesiologica Scandinavica
|March 18, 2004
PubMed

Insights

Applying Lidocaine/Prilocaine cream for 90 minutes with a 30-minute wait before intravenous cannulation significantly reduces pain in children. This improved regimen is more effective than the standard 60-minute application.

Area of Science:

  • Pediatric Anesthesiology
  • Pain Management

Background:

  • Lidocaine/Prilocaine cream is commonly used for pain relief during intravenous cannulation.
  • The standard 60-minute application is not optimal for adults, prompting investigation into improved pediatric protocols.

Purpose of the Study:

  • To determine an optimized application regimen for Lidocaine/Prilocaine cream to minimize pain during intravenous cannulation in children aged 6-12 years.

Main Methods:

  • A prospective, randomized, single-blind study involving 60 children (6-12 years).
  • Two groups: Group A (60-min cream application, immediate cannulation) and Group B (90-min cream application, followed by a 30-min interval before cannulation).
  • Pain was assessed using a faces scale.

Main Results:

  • Intravenous cannulation was significantly less painful in Group B compared to Group A (P = 0.01).
  • No significant difference was observed in cannulation success rates between the groups.

Conclusions:

  • A 90-minute application of Lidocaine/Prilocaine cream followed by a 30-minute interval is superior to the standard 60-minute application for reducing IV cannulation pain in children.
  • This modified protocol offers a more effective approach to pediatric procedural pain management.
Abstract

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