Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Urinary compounds in autism.

A Alcorn1, T Berney, K Bretherton

  • 1Department of Child and Adolescent Psychiatry, Prudhoe Hospital, Prudhoe, UK.

Journal of Intellectual Disability Research : JIDR
|March 18, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improved quantum processor logical error rates via correction and detection.

Nature·2026
Same author

Digital quantum magnetism on a trapped-ion quantum computer.

Nature·2026
Same author

Atomic origins of dislocation pinning in oxide dispersion strengthened alloys.

Journal of physics. Condensed matter : an Institute of Physics journal·2025
Same author

The Europa Imaging System (EIS) Investigation.

Space science reviews·2024
Same author

High-fidelity teleportation of a logical qubit using transversal gates and lattice surgery.

Science (New York, N.Y.)·2024
Same author

The utility of dynamic contrast-enhanced intranodal magnetic resonance lymphangiography (MRL) in the investigation of primary lymphatic anomalies.

Clinical radiology·2024
Same journal

Evaluating Scoring Mechanisms for Measuring the Stroop Effect in Individuals With Down Syndrome.

Journal of intellectual disability research : JIDR·2026
Same journal

Identifying Key Gaps: A Qualitative Exploration of Physicians-in-Training Caring for Adults With Intellectual and Developmental Disabilities.

Journal of intellectual disability research : JIDR·2026
Same journal

Preliminary Testing of the English Version of the Adolescent Screener for Intelligence and Learning Disabilities (SCIL) Among Adolescents in Nigeria.

Journal of intellectual disability research : JIDR·2026
Same journal

Predictors of Mental Healthcare Need and Utilisation Among Asian American Adolescents With Intellectual and Developmental Disabilities.

Journal of intellectual disability research : JIDR·2026
Same journal

Repetitive Behaviours in Williams Syndrome: A Cross-Cultural Comparison Between the United Kingdom and Japan.

Journal of intellectual disability research : JIDR·2026
Same journal

Validation of the Q87.11 ICD Code for Prader-Willi Syndrome.

Journal of intellectual disability research : JIDR·2026
See all related articles

This study suggests a potential biological marker for autism in prepubertal children, detectable through urinary analysis. This marker may be less apparent in children with severe learning disabilities.

Area of Science:

  • Biochemistry
  • Neurodevelopmental Disorders
  • Pediatrics

Background:

  • Previous attempts to identify specific urinary compounds in autism were discredited.
  • Emerging evidence suggested potential biochemical differences in early childhood autism, particularly in individuals without severe intellectual disability.

Purpose of the Study:

  • To investigate if autism exhibits a distinct chromatographic profile in urinary analysis.
  • To explore the potential for a biological marker for autism in prepubertal children.

Main Methods:

  • Matched cohort study involving 34 prepubertal boys with autism and two control groups.
  • Blind laboratory analysis of urine samples using chromatographic profiling.
  • Exclusion of participants with severe learning disabilities for refined analysis.

Related Experiment Videos

Main Results:

  • Initial analysis correctly identified 53% of the autism group.
  • Excluding severe learning disabilities, analysis correctly identified 77% of the autism group.
  • Control groups were misidentified at rates of 33% and 18% initially, and 8% and 18% after exclusions.

Conclusions:

  • The findings support the existence of a biological marker for autism in prepubertal children.
  • Severe learning disability may obscure or eliminate this potential urinary marker.